![]() ![]() To evaluate the long-term effects of repeated concussions in this model, we utilized a comprehensive Morris water maze (MWM) paradigm for cognitive assessments at 1 and 6 months following repeated concussive impacts in rats. A concussive impact model was previously established in our lab that produces clinically relevant signs of concussion and induced acute pathological changes in rats. 2Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, MD, United StatesĬlose-head concussive injury, as one of the most common forms of traumatic brain injury (TBI), has been shown to induce cognitive deficits that are long lasting. ![]() 1Brain Trauma Neuroprotection and Neurorestoration Branch, Center for Military Psychiatry and Neuroscience, Walter Reed Army Institute of Research, Silver Spring, MD, United States.Ying Deng-Bryant 1 *, Lai Yee Leung 1,2, Sindhu Madathil 1, Jesse Flerlage 1, Fangzhou Yang 1, Weihong Yang 1, Janice Gilsdorf 1 and Deborah Shear 1 ![]()
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